High-sugar drinks featuring artificial sweeteners may be causing gut dysbiosis, which can negatively affect overall health. High-sugar beverages, such as soda and juices, contain elevated levels of simple sugars, which can lead to an overgrowth of harmful bacteria and fungi in the gut.
Recent studies have shown that a high intake of sugars can decrease bacterial diversity, increase the relative abundance of Proteobacteria in your gut microbiome and decrease the abundance of health-promoting species [1]. These changes to microbiota can lead to compromised gut barrier functions, systemic (low-grade) inflammation, and metabolic dysregulation [1].
The microbial changes caused by high sugar intake feature similarities to the microbiota dysbiosis associated with metabolic disorders, inflammatory bowel disease (IBD) and other human disorders [1].
It is common for health-conscious individuals to substitute high-sugar drinks for sugar-free drinks featuring artificial sweeteners. An increase in artificial sweeteners can have the same effects as high-sugar drinks, with recent research linking artificial sweeteners to significant disturbances to the gut microbiome [2].
Another way high dietary sugar intake affects the gut microbiota is by altering the metabolism of gut microbes. Studies have revealed that high sugar intake can alter how gut microbes metabolize nutrients, leading to the production of short-chain fatty acids (SCFAs) such as butyrate, acetate and propionate. These SCFAs play a vital role in maintaining gut health by promoting the growth of beneficial bacteria, regulating the immune system and protecting the gut lining. However, when high amounts of sugar are consumed, the production of these SCFAs is reduced, leading to a decrease in gut health and an increased risk of chronic diseases [3,4].
To summarise, high-sugar drinks can have an adverse effect on the gut microbiome by providing a source of food for harmful bacteria, decreasing the number of beneficial bacteria, and reducing bacterial diversity. This can lead to decreased gut health and an increased risk of chronic diseases. Therefore, it is vital to be mindful of the amount of sugar consumed in drinks and to opt for healthier alternatives such as water or unsweetened probiotic juice.